It is not possible to be allergic to ozone. The body actually makes it. You can no more be allergic to ozone than you can be to oxygen. Ever hear of an allergy to oxygen? No. It cannot happen in air breathers. Contrary to what allopathic ozone doctors say, ozone is NOT a drug. It is oxygen carrying an electric charge which will boost the body's life function on many levels.
The dislike of the smell of ozone is one of the best markers of toxicity in the body. People who are clean generally love the smell.
Stop reading bad science and read my book, The Story of Ozone. Aging and disease are caused (for the most part) by a LACK OF OXIDATION in the body. Oxidation is your friend. Your life force depends on oxidation. The more oxidation in your body, the more energy you have. The more oxygen free radicals in your body, the more light your body can create. The more light created, the higher your level of functioning and intelligence. Eat a good diet with plenty of fresh vegetables and fruits, and supplemental minerals (calcium, magnesium, chromium, iron for ladies) do regular liver cleanses, do ozone daily, go out in the sun for at least 15 minutes every day, eat sardines, drink flax oil and chlorophyll and aloe, and take brewer's yeast and sublingual B12 daily. Forget everything else. Call me when you are 120.
Lung function is affected greatly by kidney function. You can keep the kidneys working better by taking flax oil every day. You can get rid of your asthma by breathing ozone bubbled through olive oil daily for a few months. These treatments would be perfectly safe for your heart. Did the doctor who diagnosed the leaky valve say the cause? Most often, there is a plaque buildup, but sometimes there is a bacterial colony. Both of which would be improved by ozone.
Not even close. When doctors around the world do their clinical trials, the control group gets oxygen, and the test group gets ozone. Invariably the results are reported as 90 - 95% effective for the test group with ozone therapy, and NO EFFECT for the control group with oxygen.
Titanium is no problem. Without knowing the other material, I cannot say, but my guess would be some type of silicone in order to have the flexibility, and the durability. If so, then no problem there. Always make sure of what material prosthetics are made before you apply ozone to that area.